Bio-medically active zinc oxide nanoparticles synthesized by using extremophilic actinobacterium, Streptomyces sp. (MA30) and its characterization

Abstract

The present study describes the synthesis of zinc oxide nanoparticles (ZnO-NPs) using an extremophilic actinobacterial cell-free extract, supplied with aqueous zinc acetate solution. Crystalline nature, morphological features, and polydispersed nanoparticles size (15–30 nm) were identified by X-ray diffraction (XRD), atomic force and electron microscopic analysis with dynamic light scattering (DLS) study. The interaction between biomolecules and ZnO-NPs was analyzed using Fourier transform infra-red spectroscopy (FT-IR). Furthermore antibacterial, antioxidant activities, and cell viability test of ZnO-NPs were systematically evaluated. The present study opens a new avenue for the actinobacterial synthesis of oxide nanoparticles.

Keywords:

• Biosynthesis
• zinc oxide
• antibacterial
• antioxidant
• Streptomyces sp

Acknowledgements

The authors are indebted to authorities of the Periyar University, Salem for providing all the necessary facilities to carry out this work.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.

Additional information

Funding

One of the authors (T. Shanmugasundaram) wishes to thank the DST, India for financial support in the form of INSPIRE Fellowship.