Lantana camara Linn root extract-mediated gold nanoparticles and their in vitro antioxidant and cytotoxic potentials

Abstract

The Lantana camara Linn root extract derived gold nanoparticles (Au NPs) were characterized by Ultraviolet-Visible spectroscopy, X-ray diffraction, fourier transform-infrared, high resolution transmission electron microscopy, selected area electron diffraction pattern and energy dispersive X-ray analyses. In DPPH assay, the inhibitory concentration (IC₅₀) of Au NPs and gallic acid was 24.17 and 5.39 μg/ml, whereas, for cytotoxicity assay, the IC₅₀ of Au NPs was 17.72 and 32.98 μg/ml on MBA-MB-231 and Vero cells, respectively. Thus, the Au NPs possess significant in vitro antioxidant and cytotoxic properties which could be considered as potential alternate for the development of anticancer drug in future.

Keywords:

• Lantana camara
• Au NPs
• HR-TEM
• DPPH
• MDA-MB-231

Acknowledgements

The authors are grateful to their host institutes for providing necessary facilities to carry out this work.

Disclosure statement

All the authors declare that they have no conflict of interests including any financial, personal, or other relationships with other people or organizations.