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Research Article

The first invasive Candida auris infection in Taiwan

ORCID Icon, , , , , , & show all
Pages 1867-1875 | Received 25 Apr 2022, Accepted 07 Jul 2022, Published online: 27 Jul 2022
 

ABSTRACT

Candida auris, a multidrug resistant pathogenic yeast, has spread worldwide and caused several outbreaks in healthcare settings. Here, we report the first case of C. auris candidemia in Taiwan in a patient with a two-month history of hospitalization in Vietnam. We performed further investigation on the isolate from the present case as well as the previously reported C. auris isolate identified from a wound in 2018 in Taiwan, which was the first case reported in Taiwan. Both C. auris isolates were found to be susceptible to fluconazole, amphotericin B, and echinocandins. Additionally, mutations in ERG11 or FKS1 were not detected in either isolate. Microsatellite genotyping revealed that both isolates belonged to the South Asian clade. In recent years, C. auris has emerged as a global concern, and differences in clades and susceptibility patterns mandate further awareness and systematic surveillance.

Acknowledgments

The authors thank Hung-Jen Tang for kindly providing the Candida auris isolate from Chi Mei Medical Center, Tainan, Taiwan.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Institutional Review Board Statement

The study was conducted in accordance with the Declaration of Helsinki, and reviewed and approved by the Institutional Review Board of Kaohsiung Medical University Hospital (IRB no. KMUHIRB-E(I)-20210303).

Informed Consent Statement

Informed consent was obtained from the patient’s next of kin.