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Abstract
Staphylococcus aureus is one of the most frequently isolated pathogens from blood stream infections, skin and soft tissue infections, hospital acquired post operative wound infections. The anti-staphylococcal activity of Pelargonium graveolens and Oliveria decumbens ethanolic extracts was evaluated by disc diffusion and microbroth dilution assays. The extracts were tested in vitro against clinical isolates of S. aureus. The antimicrobial activity of extracts varied according to the type of isolates. Clear correlation between minimal inhibitory concentration values and inhibition diameters was found. The MIC values of P. graveolens extract against clinical isolates of S. aureus were in the ranges of 0.2 – 0.8 g/L and for O. decumbens were 9.6 – 38.4 g/L. The ethanolic extract of O. decumbens had less antistaphylococcal effect than the P. graveolens extract (P<0.05).
