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Original Articles

Chemical Composition, Antimicrobial, Antioxidant and Anticancer Activity of Leaves of Syzygium benthamianum (Wight ex Duthie) Gamble

, , , &
Pages 273-278 | Received 05 Jun 2011, Accepted 28 Jun 2011, Published online: 24 Jun 2013
 

Abstract

The study was carried out on antimicrobial, antioxidant and anticancer activity of Syzygium benthamianum leaf extract. Chemical compositions of the leaf were analysed using GC/MS technique. A total of 24 compounds were identified among which 4-(4-ethylcyclohexyl)-1-pentyl-Cyclohexene (24.07 %) and Linoleic acid (15.16 %) are the major constituents. Antimicrobial activity of the leaf was observed on six bacterial and three fungal species, whose MIC values ranged from 100 to 500 μg/ml. At higher concentration, the extract exhibits higher scavenging activity (94.7 %) that was comparable with standard BHT. It was also observed that the leaf sample were able to effectively inhibit the growth of Hep 2 cells.

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