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Original Articles

Phytochemical Screening and Anti-Inflammatory Actions of Alangium villosum polyosmoides Root Extract

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Pages 99-103 | Received 17 Oct 2011, Accepted 12 Jan 2012, Published online: 24 Jun 2013
 

Abstract

The purpose of the present study was to explore phytochemical characteristics and to investigate the anti-inflammatory actions of the methanolic extract of Alangium villosum polyosmoides roots. A. villosum polyosmoides roots were characterized for phytochemical and the percentage inhibition of carrageenan induced paw oedema was studied in rats. A. villosum polyosmoides gave maximum extractive values with Methanol and the Loss on Drying value, total Ash value, acid-insoluble ash, water soluble ash values were within limits. The extract gave positive tests for Phytosterols, Triterpenes, Flavonoids, Carbohydrates and Alkaloids. The extract was free from Glycosides, Saponins, Tannins, Proteins and Amino Acids. The A. villosum polyosmoides root gave significant per cent inhibition of the maximal paw Oedema and very highly significant per cent inhibition of total paw Oedema during 6 h. This study revealed that A. villosum polyosmoides root has good anti-inflammatory actions when compared with Diclofenac sodium.

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