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Abstract
The aim of present work was to investigate antimicrobial activity of essential oil of the endemic species of Senecio belgaumensis (Wight) Cl., against human pathogenic Gram-positive, Gram-negative bacteria and fungi. The antimicrobial activity of essential oil was determined by tube dilution method. Further, bacteriostatic and bactericidal concentrations were determined for each strain that evidence quantitative analysis. The oil was effective against the microorganism Streptococcus faecalis (Gram-positive bacteria) (MIC 0.015 ± 0.002; MBC 0.025 ± 0.004) followed by Aspergillus fumigatus (MIC 0.045 ± 0.006 mg/mL; MBC 0.052 ± 0.008 mg/mL) and Aspergillus niger (MIC 0.104 ± 0.016 mg/mL; MBC 0.130 ± 0.016 mg/mL) (fungi). The oil showed bacteriostatic and bactericidal activities against all tested strains except Escherichia coli, Salmonella typhimurium and Pseudomonas aeruginosa (Gram-negative bacteria). The essential oil exhibited satisfactory antimicrobial activity, which could be used for the development of novel antimicrobial agents.