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Short Communications

Antihyperlipidemic Flavonoid Glycoside from Salvadora oleoides (Decne.)

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Pages 364-371 | Received 26 Sep 2019, Accepted 02 Nov 2019, Published online: 23 Dec 2019
 

Abstract

A flavonoid glycoside was isolated from the n-BuOH fraction of the leaves of Salvadora oleoides (decne.). The structure of the compound was elucidated by using spectroscopic methods, including UV, IR, LCMS and NMR techniques. The compound was identified as 5-hydroxy-2-(4-hydroxyphenyl) -3,7-bis ((3,4, 5-trihydroxy-6-methyltetrahydro - 2H - pyran -2-yl) oxy) - 4H-chromen-4-one reported based on interpretation of spectroscopic data. Furthermore, isolated compound was screened for their antihyperlipidemic potential at a dose of 50 mg/kg. SOD2 showed significant reduction in plasma cholesterol (76.34 mg/dl), triglyceride (88.53 mg/dl), LDL (24.52 mg/dl), VLDL (17.71 mg/dl) and increase in HDL level (34.11 mg/dl) as we know that HDL is good for health.

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