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Review Article

Psychiatric research in the Northern Finland Birth Cohort 1986 – a systematic review

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Article: 1571382 | Received 20 Jun 2018, Accepted 12 Jan 2019, Published online: 11 Feb 2019
 

ABSTRACT

The Northern Finland Birth Cohort 1986 is a large population-based birth cohort, which aims to promote health and wellbeing of the population. In this paper, we systematically review the psychiatric research performed in the cohort until today, i.e. at the age of 32 years of the cohort (2018). We conducted a systematic literature search using the databases of PubMed and Scopus and complemented it with a manual search. We found a total of 94 articles, which were classified as examining ADHD, emotional and behavioural problems, psychosis risk or other studies relating to psychiatric subjects. The articles are mainly based on two large comprehensive follow-up studies of the cohort and several substudies. The studies have often used also nationwide register data. The studies have found several early predictors for the aforementioned psychiatric outcomes, such as problems at pregnancy and birth, family factors in childhood, physical inactivity and substance use in adolescence. There are also novel findings relating to brain imaging and cognition, for instance regarding familial risk of psychosis in relation to resting state functional MRI. The Northern Finland Birth Cohort 1986 has been utilised frequently in psychiatric research and future data collections are likely to lead to new scientifically important findings.

Abbreviations: attention deficit hyperactivity disorder (ADHD); magnetic resonance imaging (MRI)

Acknowledgments

We would like to acknowledge all the participants in this study and the researchers who collected the data.

Disclosure statement

No potential conflict of interest was reported by the authors.

Supplementary material

Supplemental data for this article can be accessed here

Additional information

Funding

This work was supported by the Academy of Finland [268336]; Alfred Kordelinin Säätiö; Juho Vainion Säätiö [201610329]; Orion Research foundation; Suomen Kulttuurirahasto [00160427]; Suomen Lääketieteen Säätiö.