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Summary
A sonographically guided fine needle aspiration biopsy of a well circumscribed echodense liver nodule disclosed a hepatic localization of a malignant plasma cell dyscrasia in a 51-year-old female. On computed tomography (CT) the lesion presented as a hypodense nodule. Further examinations revealed overt non-excretory multiple myeloma with intracellular kappa chains. Differential diagnosis of an echogenic hepatic mass should thus include extramedullary plasmocytoma.