Tumor evolution: Multiple induction mechanisms for cell competition

ABSTRACT

Tumor cells often differ genetically from normal cells and from one another. Competitive interactions can occur between genetically-distinct cells, and recent studies highlight multiple examples where cell competition initiates using distinct pathways.

Keywords:

• Drosophila melanogaster
• tumor evolution
• p53
• RpS12
• Innate immunity

Disclosure or Potential Conflicts of interest

No potential conflicts of interests were disclosed

Additional information

Funding

Research supported by the National Institute of General Medical Sciences of the National Institutes of Health under award number R01GM104213.