Imitation-tumor targeting based on continuous-wave near-infrared tomography

Abstract

Continuous-wave Near-Infrared (NIR) optical spectroscopy has shown great diagnostic capability in the early tumor detection with advantages of low-cost, portable, non-invasive, and non-radiative. In this paper, Modified Lambert-Beer Theory is deployed to address the low-resolution issues of the NIR technique and to design the tumor detecting and imaging system. Considering that tumor tissues have features such as high blood flow and hypoxia, the proposed technique can detect the location, size, and other information of the tumor tissues by comparing the absorbance between pathological and normal tissues. Finally, the tumor tissues can be imaged through tomographic method. The simulation experiments prove that the proposed technique and designed system can efficiently detect the tumor tissues, achieving imaging precision within 1 mm. The work of the paper has shown great potential in the diagnosis of tumor close to body surface.

Keywords:

• Near-infrared
• tumor detection
• Lambert-Beer theory
• tomography

Disclosure statement

No potential conflicts of interest were disclosed.

Additional information

Funding

This work is sponsored by National Natural Science Foundation of China (GN: 61401117 and 61301012), and the Fundamental Research Funds for the Central Universities (Grant No. HIT. IBRSEM. 201304).