Publication Cover
Mitochondrial DNA Part A
DNA Mapping, Sequencing, and Analysis
Volume 28, 2017 - Issue 6
111
Views
1
CrossRef citations to date
0
Altmetric
Research Article

High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)

, , , , , , , , , & show all
Pages 851-854 | Received 13 Apr 2016, Accepted 31 May 2016, Published online: 10 Dec 2016
 

Abstract

Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel breeds in China and Mongolia. Due to variation of the repeat unit G(T/C)(AC)n, length heteroplasmy was detected within each camel by direct sequencing and fragment analysis. A high occurrence of mtDNA heteroplasmy, up to 100 percentages was observed in five camel populations. Our study provides the first evidence of extensive length heteroplasmy in Bactrian camels.

Disclosure statement

The authors declare that they have no competing interests.

Funding information

This work was supported by the Agricultural Science and Technology Innovation Program of China to YM (Grant No. ASTIP-IAS01), Special Fund for Basic Scientific Research of Institute of Animal Science, Chinese Academy of Agricultural Sciences to XH (Grant No. 2012cj-6) and Chinese Domestic Animal Germplasm Resources Infrastructure to YM. LJ was supported by the Elite Youth Program in Chinese Academy of Agricultural Sciences.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.