Syntheses, characterization, crystal structures, and antimicrobial activity of oxidovanadium(V) complexes with hydrazone and pyrone ligands

Abstract

A pair of new oxidovanadium(V) complexes, [VOLL¹] (1) and [VOLL²] (2), where L is the dianionic form of the hydrazone ligand N′-(2-hydroxy-3-methoxybenzylidene)-3-methylbenzohydrazide (H₂L), L¹ and L² are the deprotonated form of 3-hydroxy-2-methyl-4H-pyran-4-one (HL¹) and 3-hydroxy-2-ethyl-4H-pyran-4-one (HL²), respectively, have been prepared and characterized by elemental analyses, IR, UV-Vis, ¹H NMR and single crystal X-ray determination. The V atoms in the complexes are in octahedral coordination, with the hydrazone ligand coordinates to the metal atoms through the phenolate O, imino N, and enolate O atoms, and with the pyrone ligands through the carbonyl and hydroxyl O atoms. The effect of the compounds on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.

Keywords:

• Hydrazone
• pyrone
• vanadium complex
• crystal structure
• antimicrobial activity

Additional information

Funding

This research was supported by the Top-class foundation of Pingdingshan University (no. PXY-BSQD-2018006 and PXY-PYJJ-2018002).