Caffeine-mediated synthesis of CuO nanoparticles: characterization, morphology changes, and bactericidal activity

Abstract

This study aims the synthesis of CuO nanoparticles using caffeine as stabilizing agent by precipitation method. The effect of caffeine on the morphology of CuO NPs was studied by varying the concentrations of caffeine. The synthesized CuO NPs were characterized using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction study (XRD) scanning electron microscopy coupled with energy-dispersive X-ray diffraction (SEM-EDAX), and transmission electron microscope with selected area diffraction (TEM-SAED). The morphological study of the nanoparticles shows that the leafy particles transformed into spherical nanoparticles at higher concentration of caffeine. The synthesized CuO NPs showed antibacterial activity against pathogenic bacteria. This research support to understand the role of caffeine in the synthesis of CuO NPs and further it could be used as material for biomedical applications.

Keywords:

• Caffeine
• organic modifier
• copper oxide
• spherical nanoparticles

Acknowledgments

The authors gratefully acknowledge the authority of STIC, CUSAT, Cochin for providing the SEM and TEM images for this study. The authors thank the Director, IIT Indore for providing XPS analysis.

Disclosure statement

The authors declare that they have no conflict of interest.