Review on facile synthesis of cerium oxide nanoparticles and their biomedical applications

Abstract

This article has reviewed about one of the most potential metal oxide nanoparticles, Cerium oxide nanoparticles (CeO₂NPs) and various synthesis methods including combustion, microwave, solvothermal, sol-gel, simple co-precipitation method, spray pyrolysis, hydrothermal synthesis, microemulsion method, solvo thermal method and Green synthesis: plant mediated (Olea Europaea, Prosopis juliflora, Azadirachta indica, Petroselinum crispum, Aloe Barbadensis, Hibiscus sabdariffa), Nutrient mediated (Honey), Fungus mediated (Aspergillus niger, Humicola sp) and Biopolymer mediated (starch). CeO₂NPs catalytic properties such as superoxide dismutase mimetic (SOD) and catalase mimetic activities. Biomedical applications of CeO₂NPs such as anticancer, antiinflammatory, antioxidative, antimicrobial, antidiabetic and for the treatment of various neurodegenerative diseases are also reported.

Keywords:

• Cerium oxide nanaoparticles
• conventional synthesis
• green synthesis
• catalytic properties
• biomedical applications

Acknowledgment

We thank management of St. Pauls College of Pharmacy for their constant encouragement and support.

Disclosure statement

No potential conflict of interest was reported by the authors.

Figure 15. Mechanism of formation of Plant mediated synthesis of CeO₂ nanoparticles.^[4]

Figure 16. Possible photocatalytic mechanism for PMG degradation on citric acid -modified ultrasmall CeO₂ NPs.^[35]