Abstract
Hepatic involvement in systemic lupus erythematosus (SLE) may be due to the disease itself, but is most often associated with the use of hepatotoxic drugs, hepatic steatosis and coexistence of viral hepatitis. Cases of Budd-Chiari syndrome (BCS) associated with antiphospholipid syndrome (APS) have been reported in adults with lupus. The authors report a rare case of juvenile systemic lupus erythematosus (jSLE) associated with APS who presented BCS and subsequent progression to large regenerative nodules and hepatocellular carcinoma.
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Acknowledgements
All the authors critically revised and approved the final version of the manuscript.
Conflict of interest
None.