Acneiform eruption associated with the use of vortioxetine

ABSTRACT

Acneiform is used to describe eruptions that resemble acne vulgaris, but are not aetiologically similar. A number of drugs that can be responsible for acneiform eruptions exist. Vortioxetine is a multimodal antidepressant molecule that shows an antagonistic effect to the 5HT1D, 5HT3, and 5HT7 receptors, a partial agonistic effect to the 5HT1B receptor and a fully agonistic effect to the 5HT1A receptor, and also is an inhibitor to the serotonin transporter (SERT). In this article, we report a female patient who developed acneiform eruption during vortioxetine treatment.

KEYWORDS:

• Vortioxetine
• antidepressant
• depression
• acneiform eruption
• ldermatologic side effect
• adverse effect

Disclosure statement

No potential conflict of interest was reported by the authors.