Inflammatory and immunological changes caused by noise exposure: A systematic review

Abstract

Today, due to the growth of industries and spread of the use of various instruments and devices that produce high noise levels, it is necessary to pay more attention to the effects of exposure to noise on organs and tissues in the body. The importance of the immune system in fighting external and pathogenic factors has raised the need to consider external factors (such as harmful physical factors) and make efforts to avoid producing them. In this systematic review, 811 potentially relevant studies were found in Google Scholar, PubMed, and Web of Science databases, of which 32 different English-written articles were included in the study. The method of searching and systematically reviewing articles was based on the assessment tool of the multiple systematic reviews (AMSTAR) method. The results of this study suggested that noise could affect the function of the immune system and its components by affecting other systems and organs of the body, including the central nervous system, auditory system, circulatory system, and endocrine gland. Moreover, it can be hypothesized that noise affects immune system by producing the NADPH oxidase (Nox) and reactive oxygen species (ROS).

Keywords:

• Noise
• health
• immunology
• inflammatory
• systematic review

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Acknowledgements

The authors would like to thank the department of occupational health engineering, immunology research center and drug applied research center (DARC) of Tabriz University of Medical Sciences. This paper was extracted from a master’s thesis (Thesis Code Number: 378) by Amirreza Abouee Mehrizi, a master’s student in occupational health and safety at Tabriz University of Medical Sciences.

Compliance with ethical standards

Research involving human participants and/or animals: No humans or animals were used in this study.

Informed consent: Not associated for this study.

Disclosure statement

This article was written completely independently with no organization affiliation. The authors are responsible for publishing the content of this manuscript.