https://orcid.org/0000-0001-6548-7823
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ABSTRACT
Tetraclinis articulata is a medicinal plant distributed from northwestern Africa to southwestern Europe. This article reports previous investigations on T. articulata regarding its taxonomy, botanical description, geographical distribution, traditional use, phytochemistry, biological effects, toxicology, nutritional value, and economic interest. The search of data was based on several scientific databases such as Scopus, Wiley Online, Web of Science, Google Scholar, PubMed, ScienceDirect, SciFinder, and SpringerLink. Indeed, several biological activities were reported for T. articulata extracts and EOs, including antioxidant, antibacterial, antifungal, anticorrosion, cytotoxic, insecticidal, leishmanicidal, larvicidal, anti-inflammatory, antidiarrheal, vasorelaxant, and protective activities. Moreover, some toxicological reports indicated that T. articulata does not present any toxicity. However, other investigations regarding the toxicity, the pharmacokinetic and the pharmacodynamics of T. articulata and its major bioactive compounds are required to validate its pharmacological use. T. articulata also contains some nutritional elements such as mineral compounds, sugar and proteins which could indicate its potential use in the nutraceutical field. All these properties to T. articulata attributed a major economic interest which is used actually in the manufacture of luxury varnishes, pharmaceutical products and in other industrial uses, it is also used in powder form to prepare the surface of certain paper.
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Abdelaali Balahbib
Abdelhakim Bouyahya conceived the idea, provided guidance, reviewed the article, wrote a part of the manuscript and structured the article as per the journal guidelines. Mohammed Saber collected the data and wrote a part of the manuscript. Naoual El Menyiy organized the data, wrote a part of the manuscript and reviewed the article. Nasreddine El Omari and Abdelaali Balahbib wrote a part of the manuscript, cited the references as per the journal guidelines, and reviewed the final version of the article. Saoulajan Charfi, Hamza El Moudden, and Douae Taha wrote a part of the manuscript and reviewed the final version. Omar Belmehdi and Gokhan Zengin reviewed and revised the final version of the manuscript. Mohamed Tabyaoui and Hicham Harhar Conceived the idea and reviewed the final version of the manuscript.