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Research Article

Additional case of Ramichloridium mackenziei cerebral phaeohyphomycosis from the Middle East

, , , , , , & show all
Pages 429-433 | Published online: 09 Jul 2009
 

Abstract

In this report we describe a case of cerebral phaeohyphomycosis involving a 56-yearold Egyptian male who worked as a mason in Kuwait for 6 years. Computerized tomography scan of the brain revealed presence of a large abscess in the left occipital lobe. Aspirated pus from the abscess showed branched, septate, hyphae with light brown pigmentation. Cultured pus grew the fungus Ramichloridium mackenziei. Despite amphotericin B (1 mg kg-1 per day) therapy for 2 weeks, the patient expired. The isolate was later found to be resistant to amphotericin B (>32 μg ml-1). Antifungal susceptibility testing to other agents was also performed.

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