Abstract
Mycotic keratitis usually occurs in conjunction with trauma to the cornea. Scedosporium apiospermum, a dematiaceous fungus linked to the teleomorph Pseudallescheria boydiiis not a common agent of mycotic keratitis. A 22-year old male patient with mycotic keratitis due to S. apiospermumis presented. In in vitrosusceptibility testing, the isolate showed resistance against amphotericin B (minimum inhibitory concentration [MIC] 16 µg ml−1) but was susceptible to itraconazole (ITC) and fluconazole with MICs of 0.125 µg ml−1and 4 µg ml−1, respectively. The patient was cured clinically after ITC treatment and surgical intervention. Azoles may be superior for eliminating S. apiospermumfrom infected ocular sites.