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Abstract
In this presentation, the entire field of biosensor research and commercial applications will be covered, starting with the beginnings of developments in the 1960s, through 42 years to the present. Especially stressed are the fields of immunosensors, a technique dating back to 1964 and one that forms the most active field if research today. Finally, some of the newer biological sensors are mentioned‐antibody fragments and non‐immunoglobulin ligands.