86
Views
13
CrossRef citations to date
0
Altmetric
HPLC

Determination of Benzalkonium Bromide Homologues in Disinfection Products Using High‐Performance Liquid Chromatography

, , &
Pages 673-682 | Received 24 Aug 2004, Accepted 22 Nov 2004, Published online: 02 Feb 2007
 

Abstract

In this work, the two rapid reversed‐phase high‐performance liquid chromatographic (RP‐HPLC) methods were developed for the determination of seven homologues of benzalkonium bromide in hospital disinfectants. The first one uses column Purospher RP‐18e and mixture of methanol‐acetic acid and lithium perchlorate‐octanesulphonic acid aqueous solution as a mobile phase; the second method is performed on Waters Spherisorb Cyano column, and mobile phase consists of acetonitrile‐acetate buffer. Both techniques use UV detection at 263 nm. The time of analysis is shorter than 15 min, and limits of detection are bellow 0.005 mg/mL. The methods were successfully applied for analysis of three commercial disinfectants.

Supported by grant of Ministry of Industry and Trade (Czech Republic) FF‐P2/115. The authors thank Mrs. Martina Hrabinová for her technical help.

Notes

Supported by grant of Ministry of Industry and Trade (Czech Republic) FF‐P2/115. The authors thank Mrs. Martina Hrabinová for her technical help.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.