Synthesis of Oligosaccharide Fragments of the Lipoarabinomannan from Rhodococcus ruber*

* Dedicated to the memory of Jacques H. van Boom.

Abstract

The synthesis of two oligosaccharide fragments (1 and 2) of the lipoarabinomannan from Rhodococcus ruber is reported. Thioglycoside donors were used to assemble these glycans, which were prepared as their 8‐(methoxycarbonyl)octyl glycosides for potential incorporation into neoglycoconjugates.

* Dedicated to the memory of Jacques H. van Boom.

Keywords:

• Arabinofuranosides
• Glycosylation
• Lipoarabinomannan
• Thioglycosides

Acknowledgments

This work was supported by the Natural Sciences and Engineering Research Council of Canada, The Alberta Ingenuity Centre for Carbohydrate Science and The University of Alberta.

Notes

* Dedicated to the memory of Jacques H. van Boom.