Abstract
Some attempts toward the synthesis of novel inhibitors of glycosyl transferases are described. More successfully, the synthesis of an activated cyclopropacyclohexene and an amide and an amine of a cyclopropa‐fused pyranose are described. None of these three novel compounds proved to be a significant inhibitor of a retaining α‐glucosidase from barley.
† This paper is dedicated to the memory of Jacques H. van Boom.
Acknowledgments
K.A.S. would like to thank The University of Western Australia for a Hackett Postgraduate Scholarship. We thank Andrew Watts for helpful discussions, and Birte Svensson and Henrik Naested (Technical University of Denmark) for performing some of the inhibition studies.
Notes
† This paper is dedicated to the memory of Jacques H. van Boom.
* The designation H8/C8 has been arbitrarily assigned to the hydrogen and carbon atoms of the substituent at C‐4 of the cyclohexane.