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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 18, 2001 - Issue 4
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Original

CYCLIC RED BLOOD CELL DESTRUCTION IN THALASSEMIA

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Pages 729-736 | Received 22 Jun 2000, Accepted 19 Apr 2001, Published online: 07 Jul 2009
 

Abstract

A retrospective analysis of time series of hemoglobin (Hb) destruction of 24 children (11 males and 13 females) with thalassemia from the age of 6 to 12 years showed that the Hb destruction rate typically oscillated with an average period of 50 days. A possible relation between the periodism and the severity of the disease is also suggested. (Chronobiology International, 18(4), 729–736, 2001)

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