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Case Report

A Fatal Case of Spongiform Leukoencephalopathy Linked to “Chasing the Dragon”

, M. D., , M. D., , M. D. & , M. D.
Pages 887-891 | Published online: 30 Oct 2003
 

Abstract

Background: “Chasing the dragon” involves placing heroin on aluminum foil, heating it from below with a flame, and inhaling the pyrolysate through a straw. It has rarely been associated with the development of a progressive spongiform leukoencephalopathy. Case Report: A 43‐year‐old woman presented with 2 weeks of bizarre behavior, forgetfulness, and slowed speech and movements. Serum, cerebrospinal fluid, and head computed tomography (CT) scan were normal. The patient progressed to coma and expired during week 4 of hospital admission. The family confirmed that she “chased the dragon.” Cause of death at post mortem examination was spongiform leukoencephalopathy. Conclusion: The diagnosis of heroin pyrolysate‐induced spongiform leukoencephalopathy should be considered in a patient with a history of “chasing the dragon” and neurobehavioral changes, including confusion, apathy, cerebellar signs, and motor restlessness.

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