ENANTIOSELECTIVE FATE OF CHIRAL CHLORINATED HYDROCARBONS AND THEIR METABOLITES IN ENVIRONMENTAL SAMPLES

Abstract

Gas chromatographic enantioseparation of chiral organochlorines (α-HCH, cis- and trans-chlordane, heptachlor, heptachlor epoxide, oxychlordane, o,p′-DDT, compounds of technical toxaphene, stable atropisomeric PCBs and methylsulfonyl-PCBs) has been achieved during the last decade. For this purpose chiral stationary phases based on cyclodextrin derivatives have been applied in combination with GC/ECD, GC/MS, MDGC, and MS/MS. With these techniques methods have been developed which have been used to study the enantioselective fate of the chiral organochlorines. Changes in the enantioratios and conclusions drawn are reviewed.

Acknowledgments