DATABASES OF HUMAN HEMOGLOBIN VARIANTS AND OTHER RESOURCES AT THE GLOBIN GENE SERVER

Ross C. Hardison Department of Biochemistry and Molecular Biology, 206 Althouse Laboratory, Pennsylvania State University, University Park, PA, 16802, U.S.A.

David H. K. Chui Department of Pathology, McMaster University, Hamilton, ON L8N 3Z5, Canada

Cathy Riemer Department of Biochemistry and Molecular Biology, 206 Althouse Laboratory, Pennsylvania State University, University Park, PA, 16802, U.S.A.

Belinda Giardine Department of Biochemistry and Molecular Biology, 206 Althouse Laboratory, Pennsylvania State University, University Park, PA, 16802, U.S.A.

Heikki Lehväslaiho European Molecular Biology Laboratory Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK

Henri Wajcman Hoôpital Henri Mondor, INSERM U 468, Geéneétique Moleéculaire et Physiopathologie, Creéteil, 94010, France

Webb Miller Department of Biochemistry and Molecular Biology, 206 Althouse Laboratory, Pennsylvania State University, University Park, PA, 16802, U.S.A.

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Abstract

Building on the pioneering efforts of Professor Huisman, several different databases of hemoglobin variants have been developed, each with progressively increased capacity for sophisticated queries and prompt updating. These resources are reviewed in the context of a larger plan for providing related resources on hemoglobins, benign and pathological variation in these proteins and the genes that encode them, and the regulation of the globin genes.

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DATABASES OF HUMAN HEMOGLOBIN VARIANTS AND OTHER RESOURCES AT THE GLOBIN GENE SERVER

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DATABASES OF HUMAN HEMOGLOBIN VARIANTS AND OTHER RESOURCES AT THE GLOBIN GENE SERVER

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