RETENTION BEHAVIORS OF POLYBUTADIENE-COATED TITANIA AND COMPARISON TO BONDED PHASE ON LINEAR SOLVATION ENERGY RELATIONSHIPS

Abstract

The retention behaviors of polybutadiene-coated titania stationary phase (PBD-TiO₂) are investigated by the use of linear solvation energy relationships (LSERs) of 21 solutes. The logarithmic capacity factors measured on PBD-TiO₂ (log k′ (PBD-TiO₂)) in a methanol-water (80:20, v/v) mobile versus the solutes' four interaction descriptors, the McGowan characteristic molar volume (V_x), dipolarity/polarizability (Π₂*), effective or overall hydrogen bond donor acidity (Σα₂ ^H ) and hydrogen bond acceptor basicity (Σβ₂ ^H ) are analyzed by multiple regression analysis and compared to conventional bonded reversed stationary phase. We find that PBD-TiO₂ is very similar to conventional bonded reversed stationary phase. The descriptors, V_x, π₂* and Σβ₂ ^H are the most important parameters governing the retention, as they represent more than 96.62% of the log k′ variation. Finally, we come to the conclusion that the retention of PBD-TiO₂ is a partition mechanism.

ACKNOWLEDGMENT

The authors hope to thank the National Natural Science Foundation Commission of China for financial support, project 29575201.