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Abstract
A new simple, precise, accurate, and rapid high performance thin layer chromatography (HPTLC) method has been developed for the simultaneous determination of atenolol and nitrendipine in pharmaceutical dosage forms. The stationary phase was silica gel 60F HPTLC plates and the mobile phase was chloroform-methanol-toluene-25% ammonia (2:2.5:5.5:0.1). Detection and quantification were done densitometrically at 233 nm. The linearity ranges were 4–10 μg and 1.6–4.0 μg per spot and the percentage recoveries were 101.10 % and 98.43 % for atenolol and nitrendipine, respectively.