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Original Articles

HPLC Determination of Cilostazol in Tablets, and Its Validation

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Pages 2603-2612 | Received 03 May 2004, Accepted 28 May 2004, Published online: 11 Jun 2009
 

Abstract

A simple, rapid, and validated HPLC method has been developed for determination of cilostazol in tablets. A LiChrospher 100 RP‐18 column was used with a mobile phase consisting of methanol–acetonitrile–water (20:50:30). Quantitative evaluation was performed at 260 nm. The HPLC method is selective, precise, and accurate, and it can be used for routine analysis of the preparations in pharmaceutical industry quality control laboratories.

Acknowledgments

The authors are very grateful to Mr. Deddy Triono, Ms. Evi Umayah (Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia), and Mrs. Wiwin Farina Kartinasari (Bernofarm Pharmaceutical Company, Sidoarjo, Indonesia) for their excellent technical assistance.

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