A CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK⁺ AND TK⁻ VARICELLA ZOSTER VIRUS

C. López Universidade de Santiago, Dpto. Química Orgánica, Santiago de Compostela, E-15706, Spain

C. Balo Universidade de Santiago, Dpto. Química Orgánica, Santiago de Compostela, E-15706, Spain

J. M. Blanco Universidade de Santiago, Dpto. Química Orgánica, Santiago de Compostela, E-15706, Spain

F. Fernández Universidade de Santiago, Dpto. Química Orgánica, Santiago de Compostela, E-15706, Spain

E. De Clercq Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, B-3000, Belgium

J. Balzarini Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, B-3000, Belgium

Abstract

Several cyclobutyladenine and analogous carbonucleosides were synthesized from 1R-α-pinene and their anti-viral activity was tested. One of them (3e) showed interesting selectivity against both TK⁺ and TK⁻ VZV.

Acknowledgments

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK⁺ AND TK⁻ VARICELLA ZOSTER VIRUS

Information for

Open access

Opportunities

Help and information

A CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK+ AND TK− VARICELLA ZOSTER VIRUS

Abstract

Acknowledgments

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature

A CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK⁺ AND TK⁻ VARICELLA ZOSTER VIRUS