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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 3
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Original Articles

SYNTHESIS OF 3-ALKOXY-4-HYDROXYPHENYLACETIC ACIDS FROM METHYL 3-ALKOXYBENZOATES

Young-Sik Jung Bioorganic Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Taejon, 305-606, Korea
,
Tae-Souk Kang Bioorganic Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Taejon, 305-606, Korea
,
Jong-Cheol Lee Bioorganic Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Taejon, 305-606, Korea
,
Churl-Min Seong Bioorganic Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Taejon, 305-606, Korea
,
Won-Hun Ham College of Pharmacy, SungKyunKwan University, Suwon, 440-746, Korea
&
No-Sang Park Bioorganic Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Taejon, 305-606, Korea
Pages 455-462 | Received 22 Mar 2000, Published online: 09 Nov 2006
 
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Abstract

3-Alkoxy-4-hydroxyphenylacetic acids 4 were obtained from 3-alkoxyl-substituted methyl benzoates 1 by reductive alkylation, followed by allylic oxidation and hydrolysis.

ACKNOWLEDGMENTS

Financial support of this work by the Ministry of Science and Technology in Korea is gratefully acknowledged.

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