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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 7
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Original Articles

FLUORAPATITE/SODIUM NITRATE AS A SOLID SUPPORT FOR THE KNOEVENAGEL REACTION

Saïd Sebti Université Hassan II, Laboratoire de Chimie Organique Appliquée et Catalyse, Faculté des Sciences Ben M'Sik B.P., Casablanca, 7955, Morocco
,
Rachid Nazih Université Hassan II, Laboratoire de Chimie Organique Appliquée et Catalyse, Faculté des Sciences Ben M'Sik B.P., Casablanca, 7955, Morocco
,
Rachid Tahir Université Hassan II, Laboratoire de Chimie Organique Appliquée et Catalyse, Faculté des Sciences Ben M'Sik B.P., Casablanca, 7955, Morocco
&
Ahmed Saber Université Hassan II, Laboratoire de Chimie Organique Appliquée et Catalyse, Faculté des Sciences Ben M'Sik B.P., Casablanca, 7955, Morocco
Pages 993-999 | Accepted 05 Jun 2000, Published online: 09 Nov 2006
 
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Abstract

The Knoevenagel reaction is assisted by sodium nitrate/fluorapatite in heterogeneous media. The reaction is carried out between an activated methylene and an aldehyde at room temperature without a solvent. The yields obtained are very high.

ACKNOWLEDGMENTS

The support of the Office Chérifien des Phosphates (OCP) is gratefully acknowledged.

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