Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 14
Submit an article Journal homepage
115
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

O-BENZYLATION OF POLYPHENOLICS. PREPARATION OF 1,2,4-TRIBENZYLOXYBENZENE

Uffe Anthoni Marine Chemistry Section, Department of Chemistry, University of Copenhagen, Universitetsparken 5, Copenhagen, DK-2100, Denmark
,
Carsten Christophersen Marine Chemistry Section, Department of Chemistry, University of Copenhagen, Universitetsparken 5, Copenhagen, DK-2100, Denmark
&
Per Halfdan Nielsen Marine Chemistry Section, Department of Chemistry, University of Copenhagen, Universitetsparken 5, Copenhagen, DK-2100, Denmark
Pages 2223-2229 | Received 14 Aug 2000, Published online: 09 Nov 2006
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

The main phenolic by-products in the O-benzylation of 1,2,4-trihydroxy-or 1,2,4-triacetoxybenzene to 1,2,4-tribenzyloxybenzene have been identified as due to incomplete O-benzylation and C-benzylation. In addition, dibenzyldimethylammonium chloride is formed from DMF and benzyl chloride. The main factors controlling these reactions paths are discussed. An efficient procedure for preparing 1,2,4-tribenzyloxybenzene using NaH in DMF is reported.

Acknowledgments

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.