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Abstract
A general and practical route for the moderate yield oxidative conversion of readily accessible 1,4-dihydropyridines (1,4-DHPs) to the corresponding pyridines was described using a relatively benign oxidant, i.e. ferric chloride hexahydrate (FeCl3·6H2O). The reaction was carried out under mild and convenient condition. However, oxidation of 4-isopropyl-1,4-DHP 1b with FeCl3·6H2O afforded the dealkylated pyridine 2a.
ACKNOWLEDGMENTS
This work was supported by the Natural Science Foundation of Shaan'xi Province (2000H03).