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Abstract
Treatment of the aldoxime derived from vanilin with trichloroisocyanuric acid in the presence of olefins as dipolarophiles caused the formation of nitrile oxides and subsequent 1,3-dipolar cycloaddition forming the corresponding isoxazoline derivatives in good yields.
ACKNOWLEDGMENT
We thanks CAPES and FAPERJ for the financial support of this work, and Dr. Edson Ferreira da Silva, Mônica Zucolotto, Dr. Elisabete Cruz and Lab. NMR of IQ/UFRJ for spectral analysis.