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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 2
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Original Articles

POTENTIAL PURINE ANALOGUE ANTAGONISTS: SYNTHESIS OF NOVEL CYCLOALKANE RING-FUSED PYRAZOLO[1,5-A]PYRIMIDINES

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Pages 253-264 | Received 16 Oct 2000, Published online: 16 Aug 2006
 

ABSTRACT

A convenient route for the synthesis of new variety of pyrazolo[1,5-a]pyrimidine derivatives by the reaction of 5-aminopyrazoles with suitable unsaturated keto compounds. The structure of the reaction products were established based on the elemental analysis, spectral data (IR, 1H NMR, MS) and X-ray diffraction analysis.

ACKNOWLEDGMENT

We are indepted to Dr. Peter G. Jones, Institut fur Inorganische und Analytische Chemie, Technische Universitat Braunschweig, Germany, for the measurement of crystal structure of compound 4a.

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