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ABSTRACT
The selective synthesis of ethyl 4-(diethoxyphosphinyl)-3-oxobutanoate (7) and the utilization of its trimethylsilyl enolether (14) in a tandem desilylation Horner-Wittig condensation is illustrated.
ACKNOWLEDGMENTS
We thank mr HSC Spies for the NMR spectra and many valuable discussions and ms V Truter for the mass spectra. Financial support by the University of Stellenbosch and technical support by mr MC de Jongh and his staff is gratefully appreciated.