APPLICATION OF DEPBT FOR SYNTHESIS OF N-PROTECTED PEPTIDE ALCOHOLS AND ITS DERIVATIVES

Ping Liu Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China

Bin-yuan Sun Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China

Xiao-hua Chen Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China

Gui-ling Tian Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China

Yun-hua Ye Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing, 100871, ChinaCorrespondence[email protected]

ABSTRACT

A series of N-protected peptide alcohols and one N-glycopeptide derivative were synthesized using DEPBT. We showed that the carboxyl group selectively reacted with amino group of the amino component in the presence of unprotected hydroxy groups.

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ACKNOWLEDGMENT

This work was supported by National Natural Science Foundation of China (No. 29872002)

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APPLICATION OF DEPBT FOR SYNTHESIS OF N-PROTECTED PEPTIDE ALCOHOLS AND ITS DERIVATIVES

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APPLICATION OF DEPBT FOR SYNTHESIS OF N-PROTECTED PEPTIDE ALCOHOLS AND ITS DERIVATIVES

ABSTRACT

ACKNOWLEDGMENT

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