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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 8
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Original Articles

RAPID REDUCTION OF NITRILES TO PRIMARY AMINES WITH NICKEL BORIDE AT AMBIENT TEMPERATURECitation[1]

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Pages 1265-1269 | Received 05 Mar 2001, Published online: 16 Aug 2006
 

ABSTRACT

Reduction of a variety of nitriles to their corresponding primary amines can be achieved with nickel boride generated in situ in dry ethanol at ambient temperature. The reductions are very rapid and chemoselective.

ACKNOWLEDGMENT

Financial support by CSIR (Project No. 1 (1567)-99) EMR II, New Delhi, India for the above project is gratefully acknowledged.

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