STUDIES IN LARGE RING COMPOUNDS: SYNTHESIS OF SOME NEW MORPHANTHRINDINES AND DIAZOCINES

ABSTRACT

A novel method for the synthesis of 2 or 3-substituted 5,6-dihydro-6,11-dioxo-morphanthridines (2) involving the cyclisation of anilinic acid (1) with PPA/AcOH has been developed. A new heterocyclic system, 2 or 3-Substituted 5,6,11,12-tetrahydrodibenzo[b, f] [1,4]diazocine-6,11-diones (4) has been synthesized with excellent yields.

Keywords:

• Phthalic anhydride
• Morphanthrindines
• PPA
• Diazocine

ACKNOWLEDGMENT

We thank Dr. Y. B. Vibhute, Yeshwant Mahavidhylaya Nanded, Dr. W. N. Jadhav, Dnyanopasak College, Parbhani and Dr. P. P. Wadgaonkar, NCL, Pune for their valuable suggestions.