NOVEL DIBENZOTHIAZEPINES WITHOUT SUBSTITUTION ON THE SULFONAMIDE GROUP

Nicolas Lebegue Laboratoire de Pharmacie Chimique et Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques de Lille, 3 rue du Professeur Laguesse, B.P. 83., LILLE Cedex, 59006

Nathalie Flouquet Laboratoire de Pharmacie Chimique et Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques de Lille, 3 rue du Professeur Laguesse, B.P. 83., LILLE Cedex, 59006

Pascal Berthelot Laboratoire de Pharmacie Chimique et Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques de Lille, 3 rue du Professeur Laguesse, B.P. 83., LILLE Cedex, 59006Correspondence[email protected]

Bruno Pfeiffer ADIR, 1 rue Carle Hébert, Courbevoie Cedex, 92415

Pierre Renard ADIR, 1 rue Carle Hébert, Courbevoie Cedex, 92415

ABSTRACT

We have developed the synthesis of new thiazepine compounds bearing a non substituted sulfonamide group, which is described through two different synthetic pathways, to design new anticancer structural families.

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NOVEL DIBENZOTHIAZEPINES WITHOUT SUBSTITUTION ON THE SULFONAMIDE GROUP

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NOVEL DIBENZOTHIAZEPINES WITHOUT SUBSTITUTION ON THE SULFONAMIDE GROUP

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