A REGIOSPECIFIC SYNTHESIS OF 1-HETEROCYCLIC SUBSTITUTED 1,2,4-TRIAZOLES VIA ADDITION REACTION OF 1,2,4-TRIAZOLE WITH FUNCTIONALIZED CARBODIIMIDE

ABSTRACT

The reaction of 1,2,4-triazole with functionalized carbodiimide 2 or 6 under solid K₂CO₃ provide a convenient and regiospecific route to 1-(2-imidazolonyl)-1,2,4-triazole 4 or 1-(2-quinazolonyl)-1,2,4-triazole 8.

Keywords:

• Triazoles
• Iminophosphorane
• Imidazolinones
• Quinazolinones
• Aza-Wittig reaction

ACKNOWLEDGMENTS

We gratefully acknowledge financial support of this work by the National Natural Science Foundation of China (Project No. 20102001).