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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 22
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Original Articles

NOVEL INTRAMOLECULAR CYCLIZATION OF PYRAZOLONE KETENE S,N-ACETALS FOR THE CONSTRUCTION OF METHYLSULFANYLPYRAZOLO- [4,3-b]PYRIDINES

, , &
Pages 3509-3517 | Received 23 Jul 2001, Published online: 22 May 2009
 

ABSTRACT

A novel and efficient method for the synthesis of 6-substituted-7,7a-dihydro-1,7a-dimethyl-7-imino-2-phenyl-1H-pyrazolo[4,3-b]pyridin-3(2H)-ones via the reaction of 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one with ketene dithioacetals and ethoxy-methylenemalononitrile or ethyl ethoxymethylene-cyanoacetate followed by intramolecular cyclization of the products has been investigated.

Acknowledgments

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