Redox Isomerization of Allylic Alcohols and Amides Using Grubbs’ Catalyst

E. S. Greenwood The Chemical Laboratories, School of Chemistry, Physics & Environmental Science, University of Sussex, Falmer, Brighton, East Sussex, UK

P. J. Parsons The Chemical Laboratories, School of Chemistry, Physics & Environmental Science, University of Sussex, Falmer, Brighton, East Sussex, UK; The Chemical Laboratories, School of Chemistry, Physics & Environmental Science, University of Sussex, Falmer, Brighton, East Sussex, BN1 9QJ, UKCorrespondence[email protected] [email protected]

M. J. Young PR&D, Astra Zeneca, Severn Road, Hallen, Bristol, UK

Abstract

Commercially available Grubbs’ catalyst was found to catalyze the redox isomerization of allylic alcohols and amides under mild conditions.

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Acknowledgments

We wish to thank AstraZeneca for providing funding for MJY and ‘The Royal Commission for the Exhibition of 1851' for funding a fellowship for ESG.

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Redox Isomerization of Allylic Alcohols and Amides Using Grubbs’ Catalyst

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Redox Isomerization of Allylic Alcohols and Amides Using Grubbs’ Catalyst

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