Novel Synthesis of N-Aroylaminated Pyridones via Reaction of Ketene Dithioacetals with Cyanoaceto-N-aroylhydrazides

Galal H. Elgemeie Chemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, Egypt; Chemistry Department, Faculty of Science, Helwan University, Beni-Suef Branch, Helwan, Cairo, EgyptCorrespondence[email protected] [email protected]

Ahmed H. Elghandour Chemistry Department, Faculty of Science, Cairo University, Beni-Suef Branch, Beni-Suef, Egypt

Ali M. Elzanate Chemistry Department, Faculty of Science, Cairo University, Beni-Suef Branch, Beni-Suef, Egypt

Ghada W. Abd Elaziz Chemistry Department, Faculty of Science, Cairo University, Beni-Suef Branch, Beni-Suef, Egypt

Abstract

A novel synthesis of N-aroylamino-2-pyridones 6a–d via reaction of ketene dithioacetal 1 with cyanoaceto-N-aroylhydrazides 2a–d is reported and the synthetic potential of the method is demonstrated.

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Novel Synthesis of N-Aroylaminated Pyridones via Reaction of Ketene Dithioacetals with Cyanoaceto-N-aroylhydrazides

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Novel Synthesis of N-Aroylaminated Pyridones via Reaction of Ketene Dithioacetals with Cyanoaceto-N-aroylhydrazides

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