Abstract
2,4,6-Trichloro[1,3,5]triazine was loaded on polyethylene glycol 4000 to give a new supported reagent which was employed to carry out the liquid-phase Sonogashira coupling reaction, offering alkynyl benzamide derivatives in high yields under mild conditions by cleavage with amines.
Acknowledgments
We are grateful for the financial support from the National Science Foundation of China (Project No. 29972037) and the Postdoctoral Foundation of China.